Patient Assistance Program (PAP) – Entyvio®

Access Accelerated
Takeda's Patient Assistance Program (PAP) for Entyvio was also launched to address affordability barriers for patients diagnosed with ulcerative colitis and Crohn's disease in low to middle income countries.
Increase sustainable access to our innovative medicines for complex and rare diseases, addressing affordability barriers. Planning, monitoring, and evaluating the program.
Private Foundation or Development Organization 1
Professional Services 1
Local NGOs 1
  • To address affordability barriers for patients diagnosed with ulcerative colitis and Crohn’s disease.

Health needs and challenges

The past decade has seen major public health gains and scientific breakthroughs in the discovery of new medicines, but across the world, many people still lack access to the treatment and medicines they need, especially for very severe diseases including many forms of cancers and other NCDs. Hard to diagnose, treat and manage, NCDs also have significant affordability barriers and the treatment can be lifelong.

Inflammatory Bowel Disease (IBD) is a disease with a significant impact on individuals’ ability to be productive and has a corresponding impact on family life – this is particularly the case with ulcerative colitis and Crohn’s disease which significantly impact patients’ day to day lives.

How the program and partnership activity is addressing the needs and challenges

Our Patient Assistance Program (PAP) for Entyvio was also launched in 2017, to address affordability barriers for patients diagnosed with ulcerative colitis and Crohn’s disease. Through an independent delivery partner, Axios International, we have adopted an independent and confidential means-based assessment tool to assess patients’ ability to contribute to their medication costs, and then determine the appropriate individual payment scheme for each patient.

This ensures patients pay only what they can afford, and are able to complete their entire course of treatment even if they cannot pay for it in full. Through our delivery partner, we also provide personalized support including ongoing follow-up from program staff to ensure adherence to their treatment plan and their physician’s recommendations – improving the quality of care and efficacy of the treatment.

Takeda’s PAPs are sustainable so our innovative medicines reach as many patients as possible, and are tailored to each country to address a country’s economic context and local healthcare provisions. They use different collaborative models where patients, Takeda, and at times local authorities, foundations, medical associations, charities and other parties, share the cost of treatment. In select cases for patients with no ability to pay, we explore routes for them to access medicines included in our PAPs, through additional financial support from local medical societies, charities, and NGOs.

Results and milestones

Takeda’s Entyvio® PAP has helped 243 patients (as of 31 December 2019).


Geographic Reach
  • Americas
  • Eastern Mediterranean
  • Europe
  • South-East Asia
  • Western Pacific
See Where
Disease Area
  • Non-communicable diseases
See Disease Areas
SGDs the partnership contributes to
SDG 3: Good health and well-being
  1. 3.4: NCDs (including mental health)
  2. 3.8: Achieve universal health coverage
SDG 17: Partnerships for the goals 
Partner organizations
Private Foundation or Development Organization
Pilipinas Shell Foundation

Axios International works in partnership with Pilipinas Shell Foundation Inc., the social arm of Shell companies in Philippines (SciP) to manage the program in the Philippines.

Professional Services

Product requirement forecasting for both purchased and FOC packs. Day-to-day management of the program. Patients’ application review and actively promote the program to increase its awareness and provide communication support for physicians and patients who ask to learn more about the program. Ensure timely delivery and management of FOC drugs. Monitoring and Evaluation through monthly reports and analysis of program data. AE Reporting and reconciliations

Local NGOs
Charitable Fund I Will

Axios works in partnership with the local charity, to manage the program in the Ukraine.